In chronic myelogenous leukemia (CML), the white blood cells that are affected are a specific kind called myeloid cells, or myeloblasts.CML is uncommon in children. CML can occur over a period of months or years.

In nearly all cases, it's not known what causes leukemia. In the majority of leukemias, gene mutations and chromosome abnormalities in the leukemia cells occur sporadically (by chance). The abnormalities found in leukemia cells are not found in the other cells of the body, but if some one has CML, they may have other chromosome abnormalities. CML is often accompanied by a specific type of chromosome rearrangement: Part of chromosome #9 breaks off and attaches itself to chromosome #22.There is an exchange of genetic material between these two chromosomes. This rearrangement changes the position and functions of certain genes, which results in uncontrolled cell growth.

Heart disease is a term that includes several more specific heart conditions. The most common heart disease in the US is coronary artery disease (CAD). CAD occurs when the arteries that supply blood to the heart muscle become hardened and narrowed due to the buildup of plaque. The narrowing and buildup of plaques is called atherosclerosis. Plaques are a mixture of fatty and other substances including cholesterol and other lipids. Blood flow to the heart is reduced, which reduces oxygen to the heart muscle. This can lead to heart attack. Other heart conditions include angina, heart failure, and arrhythmias. Find out more about heart diseases.

The National Heart Attack Alert Program notes these major symptoms of a heart attack: Chest discomfort. Most heart attacks involve discomfort in the center of the chest that lasts for more than a few minutes, or goes away and comes back. The discomfort can feel like uncomfortable pressure, squeezing, fullness, or pain. Discomfort in other areas of the upper body. This can include pain or discomfort in one or both arms, the back, neck, jaw, or stomach. Shortness of breath. This often comes along with chest discomfort. But it also can occur before chest discomfort. Other symptoms. These may include breaking out in a cold sweat or experiencing nausea or light-headedness.

The two types of diabetes, insulin-dependent (type 1) and noninsulin-dependent (type 2), are different disorders. While the causes, short-term effects, and treatments for the two types differ, both can cause the same long-term health problems. Both types also affect the body's ability to use digested food for energy. Diabetes doesn't interfere with digestion, but it does prevent the body from using an important product of digestion, glucose (commonly known as sugar), for energy. After a meal the digestive system breaks some food down into sugar. The blood carries the sugar throughout the body, causing blood sugar levels to rise. In response to this rise the hormone insulin is released into the bloodstream to signal the body tissues to metabolize or burn the sugar for fuel, causing blood sugar levels to return to normal. A gland called the pancreas, found just behind the stomach, makes insulin. Sugar the body doesn't use right away goes to the liver, muscle, or fat for storage. In someone with diabetes, this process doesn't work correctly. In people with type 1 diabetes, the pancreas doesn't produce insulin. This condition usually begins in childhood. People with this kind of diabetes must have daily insulin injections to survive. In people with type 2 diabetes the pancreas usually produces some insulin, but the body doesn't respond very well to the insulin signal and, therefore, doesn't metabolize the sugar properly, a condition called insulin resistance. Insulin resistance is an important factor in type 2 diabetes. Points to Remember Diabetes interferes with the body's use of food for energy. While type 1 and type 2 diabetes are different disorders, they can cause the same complications.

The symptoms of diabetes may begin gradually and can be hard to identify at first. They may include fatigue, a sick feeling, frequent urination, especially at night, and excessive thirst. When there is extra sugar in blood, one way the body gets rid of it is through frequent urination. This loss of fluids causes extreme thirst. Other symptoms may include sudden weight loss, blurred vision, and slow healing of skin, gum, and urinary tract infections. Women may notice genital itching. A doctor also may suspect a patient has diabetes if the person has health problems related to diabetes. For instance, heart disease, changes in vision, numbness in the feet and legs, or sores that are slow to heal, may prompt a doctor to check for diabetes. These symptoms do not mean a person has diabetes, but anyone who has these problems should see a doctor. Points to Remember The symptoms of diabetes can develop gradually and may be hard to identify at first. Symptoms may include feeling tired or ill, excessive thirst, frequent urination, sudden weight loss, blurred vision, slow healing of infections, and genital itching.

Domestic violence is a pattern of coercive, controlling behavior that can include physical abuse, emotional or psychological abuse, sexual abuse or financial abuse (using money and financial tools to exert control). Domestic violence is a pervasive, life-threatening crime that affects millions of individuals across the United States regardless of age, economic status, race, religion or education. High-profile cases of domestic violence will attract headlines, but thousands of people experience domestic abuse every day. They come from all walks of life. In a 24-hour survey, NNEDV found that U.S. domestic violence programs served nearly 65,321 victims and answered more than 23,045 crisis hotline calls in one day alone. Batterers make it very difficult for victims to escape relationships. Sadly, many survivors suffer from abuse for decades. It's important for survivors to know that the abuse is not their fault, and they are not alone. Help is available for those who suffer from domestic violence.

Survivors have many options, from obtaining a protection order to staying in a shelter, or exploring options through support group or anonymous calls to a local domestic violence shelter or hotline program. There is hope for victims, and they are not alone. There are thousands of local shelters across the United States that provide safety, counseling, legal help, and other resources for victims and their children. Information and support is available for victims of abuse, their friends and family: If you are in danger, call 911, a local hotline or a national hotline. NNEDV's Web site has important safety tips andresources. U.S. National Domestic Violence Hotline provides confidential and anonymous support by phone 1-800-799-7233 or TTY 1-800-787-3224 U.S. National Teen Dating Abuse Hotline: Love Is Repect: provides teens and young adults confidential and anonymous support by phone 1-866-331-9474 or online real-time chat. Women's Law has legal information and resources for victims. The National Resource Center on Domestic Violence has information for survivors on the Domestic Violence Awareness Project Web site. The Allstate Foundation has resources to end financial abuse at: Click To Empower. Before using online resources, know that your computer or phone may not be safe. Some abusers are misusing technology to stalk and track all of a partner's activities.